How far can Botox migrate?
Botox and the other neurotoxins can migrate as long as they have not bound to the nerve, I.e. the time it takes it to work in you.
Botox stays only where injected, it does not roam through the body. "If I inject it in your face, it's not going to work [or show up in] your toe," says Rowe. "It does not have a systemic effect." However, it may migrate up to 3 cm from where it was injected.
A rare but potentially serious side effect of Botox injections is known as “migration.” According to the Journal of Neuroscience, this happens when the injectable Botox travels from the injection site into other facial muscles, and even the brain. The condition can lead to paralysis and other complications.
Answer: Botox Migration
Botox only starts acting after 3-4 days even where it is desired to act. The results start showing only after 7 days. So even if the Botox migrates to a wrong place, the results will start showing only after 4 -7 days. Botox is temporary and starts loosing its effect after 6 months.
Yes, provided you wait at least four hours before lying down. Botox® takes a few hours to settle into place, so lying down straightaway could cause it to migrate to other muscles in your face and increase the risk of complications.
When Botox migrates to either the forehead or the area between the eyes, this can result in a droopy eyelid. One reason people choose Botox may be to reduce the appearance of forehead or vertical frown lines.
The botox can migrate either at the time of injection or for a little while afterwards. The effect may only come on after days to 2 weeks later as the botox starts to work. The greater the volume injected the greater the risk of migration.
Three to four months after the injections, you'll probably find that the effects of your BOTOX treatment are starting to wane. Gradually, fine lines and wrinkles return to their previous state, although it may take several months before your face returns to its pre-treatment appearance.
Botulinum toxin can spread to a distance of 30–45 mm from the injected muscles to the adjacent muscles, even if these muscles are separated by fasciae. Neck muscles are prone to diffusion of botulinum toxin, and paralysis of the wrong muscles leads to dysphonia, dysphagia or dystonia.
Your Botox will be injected into your facial muscles, so until it settles into the muscle tissue, it has a greater chance of migrating to unwanted areas. Exercise can raise your blood pressure and induce sweating, which can make the Botox migrate.
Can exercise cause Botox to migrate?
After getting Botox, it's important to avoid too many changes in head position. Doing so could also cause the Botox to migrate. This is a common occurrence even with low-impact exercises, such as yoga or Pilates — meaning that you might be one Downward Dog away from less-than-desired results.
Muscle-paralyzing drug can move from the skin to the brain
Researchers have found that botulinum neurotoxin type A--more commonly known as Botox--can migrate into the central nervous system after it's injected into the skin.

Thank you for posting your interesting question. It is safe to workout 24 hours after your forehead, crow's feet and glabella areas without concern for Botox spread or bruising. For optimal results, I recommend that you continue to see your Board Certified Plastic Surgeon for your Botox injections.
Three to four months after the injections, you'll probably find that the effects of your BOTOX treatment are starting to wane. Gradually, fine lines and wrinkles return to their previous state, although it may take several months before your face returns to its pre-treatment appearance.
Botulinum toxin can spread to a distance of 30–45 mm from the injected muscles to the adjacent muscles, even if these muscles are separated by fasciae. Neck muscles are prone to diffusion of botulinum toxin, and paralysis of the wrong muscles leads to dysphonia, dysphagia or dystonia.
If you get hot enough to sweat in the first 24 hours after your injections, be careful not to press or rub your face where you were injected. Again, this can cause the Botox to migrate to unwanted areas. Use a soft paper towel or napkin to gently absorb the sweat without making firm contact with the skin.
Muscle-paralyzing drug can move from the skin to the brain
Researchers have found that botulinum neurotoxin type A--more commonly known as Botox--can migrate into the central nervous system after it's injected into the skin.